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A novel immunodeficient NOD.SCID-rd1 mouse model of retinitis pigmentosa to investigate potential therapeutics and pathogenesis of retinal degeneration

Retinitis pigmentosa (RP) is a common retinal degeneration disease caused by mutation in any gene of the photo transduction cascade and results in photoreceptor dystrophy. Over decades, several animal models have been used to address the need for the elucidation of effective therapeutics and factors...

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Detalles Bibliográficos
Autores principales: Mishra, Alaknanda, Das, Barun, Nath, Madhu, Iyer, Srikanth, Kesarwani, Ashwani, Bhattacharjee, Jashdeep, Arindkar, Shailendra, Sahay, Preeti, Jain, Kshama, Sahu, Parul, Sinha, Prakriti, Velpandian, Thirumurthy, Nagarajan, Perumal, Upadhyay, Pramod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399550/
https://www.ncbi.nlm.nih.gov/pubmed/28258056
http://dx.doi.org/10.1242/bio.021618