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Towards trans-diagnostic mechanisms in psychiatry: neurobehavioral profile of rats with a loss-of-function point mutation in the dopamine transporter gene

The research domain criteria (RDoC) matrix has been developed to reorient psychiatric research towards measurable behavioral dimensions and underlying mechanisms. Here, we used a new genetic rat model with a loss-of-function point mutation in the dopamine transporter (DAT) gene (Slc6a3_N157K) to sys...

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Detalles Bibliográficos
Autores principales: Vengeliene, Valentina, Bespalov, Anton, Roßmanith, Martin, Horschitz, Sandra, Berger, Stefan, Relo, Ana L., Noori, Hamid R., Schneider, Peggy, Enkel, Thomas, Bartsch, Dusan, Schneider, Miriam, Behl, Berthold, Hansson, Anita C., Schloss, Patrick, Spanagel, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399565/
https://www.ncbi.nlm.nih.gov/pubmed/28167616
http://dx.doi.org/10.1242/dmm.027623