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Towards trans-diagnostic mechanisms in psychiatry: neurobehavioral profile of rats with a loss-of-function point mutation in the dopamine transporter gene
The research domain criteria (RDoC) matrix has been developed to reorient psychiatric research towards measurable behavioral dimensions and underlying mechanisms. Here, we used a new genetic rat model with a loss-of-function point mutation in the dopamine transporter (DAT) gene (Slc6a3_N157K) to sys...
Autores principales: | Vengeliene, Valentina, Bespalov, Anton, Roßmanith, Martin, Horschitz, Sandra, Berger, Stefan, Relo, Ana L., Noori, Hamid R., Schneider, Peggy, Enkel, Thomas, Bartsch, Dusan, Schneider, Miriam, Behl, Berthold, Hansson, Anita C., Schloss, Patrick, Spanagel, Rainer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399565/ https://www.ncbi.nlm.nih.gov/pubmed/28167616 http://dx.doi.org/10.1242/dmm.027623 |
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