A Drosophila model of myeloproliferative neoplasm reveals a feed-forward loop in the JAK pathway mediated by p38 MAPK signalling

Myeloproliferative neoplasms (MPNs) of the Philadelphia-negative class comprise polycythaemia vera, essential thrombocythaemia and primary myelofibrosis (PMF). They are associated with aberrant numbers of myeloid lineage cells in the blood, and in the case of overt PMF, with development of myelofibr...

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Detalles Bibliográficos
Autores principales: Terriente-Félix, Ana, Pérez, Lidia, Bray, Sarah J., Nebreda, Angel R., Milán, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399568/
https://www.ncbi.nlm.nih.gov/pubmed/28237966
http://dx.doi.org/10.1242/dmm.028118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399568/
https://www.ncbi.nlm.nih.gov/pubmed/28237966
http://dx.doi.org/10.1242/dmm.028118

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