Cargando…

MAPK signaling pathways and HDAC3 activity are disrupted during differentiation of emerin-null myogenic progenitor cells

Mutations in the gene encoding emerin cause Emery–Dreifuss muscular dystrophy (EDMD). Emerin is an integral inner nuclear membrane protein and a component of the nuclear lamina. EDMD is characterized by skeletal muscle wasting, cardiac conduction defects and tendon contractures. The failure to regen...

Descripción completa

Detalles Bibliográficos
Autores principales: Collins, Carol M., Ellis, Joseph A., Holaska, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399572/
https://www.ncbi.nlm.nih.gov/pubmed/28188262
http://dx.doi.org/10.1242/dmm.028787