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Downregulation of mitochondrial cyclooxygenase-2 inhibits the stemness of nasopharyngeal carcinoma by decreasing the activity of dynamin-related protein 1

Cancer stem cells (CSCs) are a small subset of malignant cells, possessing stemness, with strong tumorigenic capability, conferring resistance to therapy and leading to the relapse of nasopharyngeal carcinoma (NPC). Our previous study suggested that cyclooxygenase-2 (COX-2) would be a novel target f...

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Detalles Bibliográficos
Autores principales: Zhou, Teng-Jian, Zhang, Shi-Li, He, Cheng-Yong, Zhuang, Qun-Ying, Han, Pei-Yu, Jiang, Sheng-Wei, Yao, Huan, Huang, Yi-Jun, Ling, Wen-Hua, Lin, Yu-Chun, Lin, Zhong-Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399601/
https://www.ncbi.nlm.nih.gov/pubmed/28435473
http://dx.doi.org/10.7150/thno.17647