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Adiponectin Deficiency Impairs Maternal Metabolic Adaptation to Pregnancy in Mice

Hypoadiponectinemia has been widely observed in patients with gestational diabetes mellitus (GDM). To investigate the causal role of hypoadiponectinemia in GDM, adiponectin gene knockout (Adipoq(−/−)) and wild-type (WT) mice were crossed to produce pregnant mouse models with or without adiponectin d...

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Detalles Bibliográficos
Autores principales: Qiao, Liping, Wattez, Jean-Sebastien, Lee, Samuel, Nguyen, Amanda, Schaack, Jerome, Hay, William W., Shao, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399613/
https://www.ncbi.nlm.nih.gov/pubmed/28073830
http://dx.doi.org/10.2337/db16-1096