Oxidized phagosomal NOX2 complex is replenished from lysosomes

In dendritic cells, the NADPH oxidase 2 complex (NOX2) is recruited to the phagosomal membrane during antigen uptake. NOX2 produces reactive oxygen species (ROS) in the lumen of the phagosome that kill ingested pathogens, delay antigen breakdown and alter the peptide repertoire for presentation to T...

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Detalles Bibliográficos
Autores principales: Dingjan, Ilse, Linders, Peter T. A., van den Bekerom, Luuk, Baranov, Maksim V., Halder, Partho, ter Beest, Martin, van den Bogaart, Geert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399780/
https://www.ncbi.nlm.nih.gov/pubmed/28202687
http://dx.doi.org/10.1242/jcs.196931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399780/
https://www.ncbi.nlm.nih.gov/pubmed/28202687
http://dx.doi.org/10.1242/jcs.196931

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