Cargando…

Oxidized phagosomal NOX2 complex is replenished from lysosomes

In dendritic cells, the NADPH oxidase 2 complex (NOX2) is recruited to the phagosomal membrane during antigen uptake. NOX2 produces reactive oxygen species (ROS) in the lumen of the phagosome that kill ingested pathogens, delay antigen breakdown and alter the peptide repertoire for presentation to T...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dingjan, Ilse, Linders, Peter T. A., van den Bekerom, Luuk, Baranov, Maksim V., Halder, Partho, ter Beest, Martin, van den Bogaart, Geert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399780/ https://www.ncbi.nlm.nih.gov/pubmed/28202687 http://dx.doi.org/10.1242/jcs.196931

Ejemplares similares

SWAP70 is a universal GEF-like adaptor for tethering actin to phagosomes
por: Baranov, Maksim V., et al.
Publicado: (2018)

VAMP8-mediated NOX2 recruitment to endosomes is necessary for antigen release
por: Dingjan, Ilse, et al.
Publicado: (2017)

SWAP70 Organizes the Actin Cytoskeleton and Is Essential for Phagocytosis
por: Baranov, Maksim V., et al.
Publicado: (2016)

Human Monocyte-Derived Dendritic Cells Produce Millimolar Concentrations of ROS in Phagosomes Per Second
por: Paardekooper, Laurent M., et al.
Publicado: (2019)

Reaching for far-flung antigen: How solid-core podosomes of dendritic cells transform into protrusive structures
por: Baranov, Maksim V, et al.
Publicado: (2014)

Fluorescence Lifetime Imaging of pH along the Secretory Pathway
por: Linders, Peter T. A., et al.
Publicado: (2022)

Stx5-Mediated ER-Golgi Transport in Mammals and Yeast
por: Linders, Peter TA, et al.
Publicado: (2019)

Visualizing Intracellular SNARE Trafficking by Fluorescence Lifetime Imaging Microscopy
por: Verboogen, Daniëlle R. J., et al.
Publicado: (2017)

Sugary Logistics Gone Wrong: Membrane Trafficking and Congenital Disorders of Glycosylation
por: Linders, Peter T. A., et al.
Publicado: (2020)

The Phosphoinositide Kinase PIKfyve Promotes Cathepsin-S-Mediated Major Histocompatibility Complex Class II Antigen Presentation
por: Baranov, Maksim V., et al.
Publicado: (2018)

Irregular particle morphology and membrane rupture facilitate ion gradients in the lumen of phagosomes
por: Baranov, Maksim V., et al.
Publicado: (2022)

Radical Stress Is More Cytotoxic in the Nucleus than in Other Organelles
por: Paardekooper, Laurent M., et al.
Publicado: (2019)

The PIKfyve Inhibitor Apilimod: A Double-Edged Sword against COVID-19
por: Baranov, Maksim V., et al.
Publicado: (2020)

Secretory vesicles of immune cells contain only a limited number of interleukin 6 molecules
por: Verboogen, Daniëlle R. J., et al.
Publicado: (2018)

Interleukin-6 secretion is limited by self-signaling in endosomes
por: Verboogen, Daniëlle R J, et al.
Publicado: (2018)

Fluorescence Lifetime Imaging Microscopy reveals rerouting of SNARE trafficking driving dendritic cell activation
por: Verboogen, Daniëlle Rianne José, et al.
Publicado: (2017)

Ethylene, an early marker of systemic inflammation in humans
por: Paardekooper, Laurent M., et al.
Publicado: (2017)

Lipid peroxidation causes endosomal antigen release for cross-presentation
por: Dingjan, Ilse, et al.
Publicado: (2016)

Editorial: Signaling Proteins for Endosomal and Lysosomal Function
por: Capelluto, Daniel G. S., et al.
Publicado: (2021)

Modulation of Immune Responses by Particle Size and Shape
por: Baranov, Maksim V., et al.
Publicado: (2021)

Transmembrane Helices Are an Over-Presented and Evolutionarily Conserved Source of Major Histocompatibility Complex Class I and II Epitopes
por: Bilderbeek, Richèl J. C., et al.
Publicado: (2022)

Modulation of phagosome-lysosome fusion in mouse macrophages
Publicado: (1981)

Better Together: Current Insights Into Phagosome-Lysosome Fusion
por: Nguyen, Jenny A., et al.
Publicado: (2021)

What makes (hydroxy)chloroquine ineffective against COVID-19: insights from cell biology
por: Altulea, Dania, et al.
Publicado: (2021)

Acidification of phagosomes is initiated before lysosomal enzyme activity is detected
Publicado: (1983)

Phagosome-lysosome fusion is a calcium-independent event in macrophages
Publicado: (1996)

Phagosome-lysosome fusion inhibited by algal symbionts of Hydra viridis
Publicado: (1982)

Sequential actions of phosphatidylinositol phosphates regulate phagosome-lysosome fusion
por: Jeschke, Andreas, et al.
Publicado: (2018)

Phagosome resolution regenerates lysosomes and maintains the degradative capacity in phagocytes
por: Lancaster, Charlene E., et al.
Publicado: (2021)

RESPONSE OF CULTURED MACROPHAGES TO MYCOBACTERIUM TUBERCULOSIS, WITH OBSERVATIONS ON FUSION OF LYSOSOMES WITH PHAGOSOMES
por: Armstrong, J. A., et al.
Publicado: (1971)

Phorbol myristate acetate stimulates phagosome-lysosome fusion in mouse macrophages
Publicado: (1981)

Phagosome-lysosome fusion. Characterization of intracellular membrane fusion in mouse macrophages
Publicado: (1980)

Modulation of Macrophage Activities in Proliferation, Lysosome, and Phagosome by the Nonspecific Immunostimulator, Mica
por: Jung, Myunghwan, et al.
Publicado: (2015)

Katnip is needed to maintain microtubule function and lysosomal delivery to autophagosomes and phagosomes
por: Starling, Georgina P., et al.
Publicado: (2023)

The Roles of Phospholipase A(2) in Phagocytes
por: Dabral, Deepti, et al.
Publicado: (2021)

Ca(2+) and synaptotagmin VII–dependent delivery of lysosomal membrane to nascent phagosomes
por: Czibener, Cecilia, et al.
Publicado: (2006)

Differential and sequential delivery of fluorescent lysosomal probes into phagosomes in mouse peritoneal macrophages
Publicado: (1987)

Dynein Clusters into Lipid Microdomains on Phagosomes to Drive Rapid Transport toward Lysosomes
por: Rai, Ashim, et al.
Publicado: (2016)

Hypoxia potentiates monocyte-derived dendritic cells for release of tumor necrosis factor α via MAP3K8
por: Paardekooper, Laurent M., et al.
Publicado: (2018)

Inhibition of phagosome-lysosome fusion in macrophages by certain mycobacteria can be explained by inhibition of lysosomal movements observed after phagocytosis
Publicado: (1987)

Cannot write session to /tmp/vufind_sessions/sess_64g4rj4ubejgb9chrinrca8kjb