Functional RNAs: combined assembly and packaging in VLPs

We describe here a one pot RNA production, packaging and delivery system based on bacteriophage Qβ. We demonstrate a method for production of a novel RNAi scaffold, packaged within Qβ virus-like particles (VLPs). The RNAi scaffold is a general utility chimera that contains a functional RNA duplex wi...

Descripción completa

Detalles Bibliográficos
Autores principales: Fang, Po-Yu, Gómez Ramos, Lizzette M., Holguin, Stefany Y., Hsiao, Chiaolong, Bowman, Jessica C., Yang, Hung-Wei, Williams, Loren Dean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399791/
https://www.ncbi.nlm.nih.gov/pubmed/27903913
http://dx.doi.org/10.1093/nar/gkw1154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399791/
https://www.ncbi.nlm.nih.gov/pubmed/27903913
http://dx.doi.org/10.1093/nar/gkw1154

Ejemplares similares