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Functional RNAs: combined assembly and packaging in VLPs

We describe here a one pot RNA production, packaging and delivery system based on bacteriophage Qβ. We demonstrate a method for production of a novel RNAi scaffold, packaged within Qβ virus-like particles (VLPs). The RNAi scaffold is a general utility chimera that contains a functional RNA duplex wi...

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Detalles Bibliográficos
Autores principales:	Fang, Po-Yu, Gómez Ramos, Lizzette M., Holguin, Stefany Y., Hsiao, Chiaolong, Bowman, Jessica C., Yang, Hung-Wei, Williams, Loren Dean
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399791/ https://www.ncbi.nlm.nih.gov/pubmed/27903913 http://dx.doi.org/10.1093/nar/gkw1154

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