An in vitro fluorescence based study of initiation of RNA synthesis by influenza B polymerase

Influenza polymerase replicates, via a complementary RNA intermediate (cRNA), and transcribes the eight viral RNA (vRNA) genome segments. To initiate RNA synthesis it is bound to the conserved 5΄ and 3΄ extremities of the vRNA or cRNA (the ‘promoter’). 5΄-3΄ base-pairing in the distal promoter regio...

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Detalles Bibliográficos
Autores principales: Reich, Stefan, Guilligay, Delphine, Cusack, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399792/
https://www.ncbi.nlm.nih.gov/pubmed/28126917
http://dx.doi.org/10.1093/nar/gkx043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399792/
https://www.ncbi.nlm.nih.gov/pubmed/28126917
http://dx.doi.org/10.1093/nar/gkx043

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