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An in vitro fluorescence based study of initiation of RNA synthesis by influenza B polymerase
Influenza polymerase replicates, via a complementary RNA intermediate (cRNA), and transcribes the eight viral RNA (vRNA) genome segments. To initiate RNA synthesis it is bound to the conserved 5΄ and 3΄ extremities of the vRNA or cRNA (the ‘promoter’). 5΄-3΄ base-pairing in the distal promoter regio...
Autores principales: | Reich, Stefan, Guilligay, Delphine, Cusack, Stephen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399792/ https://www.ncbi.nlm.nih.gov/pubmed/28126917 http://dx.doi.org/10.1093/nar/gkx043 |
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