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The combination of direct and paired link graphs can boost repetitive genome assembly

Currently, most paired link based scaffolding algorithms intrinsically mask the sequences between two linked contigs and bypass their direct link information embedded in the original de Bruijn assembly graph. Such disadvantage substantially complicates the scaffolding process and leads to the inabil...

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Detalles Bibliográficos
Autores principales: Shi, Wenyu, Ji, Peifeng, Zhao, Fangqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399794/
https://www.ncbi.nlm.nih.gov/pubmed/27924003
http://dx.doi.org/10.1093/nar/gkw1191