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The combination of direct and paired link graphs can boost repetitive genome assembly
Currently, most paired link based scaffolding algorithms intrinsically mask the sequences between two linked contigs and bypass their direct link information embedded in the original de Bruijn assembly graph. Such disadvantage substantially complicates the scaffolding process and leads to the inabil...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399794/ https://www.ncbi.nlm.nih.gov/pubmed/27924003 http://dx.doi.org/10.1093/nar/gkw1191 |