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Hepatitis C virus NS4B protein induces epithelial-mesenchymal transition by upregulation of Snail

BACKGROUND: Chronic hepatitis C virus (HCV) infection is an important cause of hepatocellular carcinoma (HCC). Epithelial to mesenchymal transition (EMT) is a key process associated with tumor metastasis and poor prognosis. HCV infection, HCV core and NS5A protein could induce EMT process, but the r...

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Detalles Bibliográficos
Autores principales: Hu, Bicheng, Xie, Shenggao, Hu, Yuqian, Chen, Wen, Chen, Xiaofan, Zheng, Yi, Wu, Xinxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399819/
https://www.ncbi.nlm.nih.gov/pubmed/28431572
http://dx.doi.org/10.1186/s12985-017-0737-1