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A single dose of epidermicin NI01 is sufficient to eradicate MRSA from the nares of cotton rats

Objectives: To investigate the efficacy of a potent novel antimicrobial protein of mass 6 kDa, epidermicin NI01, for eradicating the nasal burden of MRSA in a cotton rat (Sigmodon hispidus) model. Methods: MRSA strain ATCC 43300 was used to establish a robust colonization of cotton rat nares. This m...

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Detalles Bibliográficos
Autores principales: Halliwell, Samantha, Warn, Peter, Sattar, Abdul, Derrick, Jeremy P., Upton, Mathew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400076/
https://www.ncbi.nlm.nih.gov/pubmed/27999015
http://dx.doi.org/10.1093/jac/dkw457