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In vitro activity of the novel echinocandin CD101 at pH 7 and 4 against Candida spp. isolates from patients with vulvovaginal candidiasis

Background: The novel echinocandin CD101 has stability properties amenable to topical formulation for use in the treatment of acute vulvovaginal candidiasis (VVC) and recurrent VVC (RVVC). CD101 has demonstrated potent antifungal activity at pH 7, but assessment of its activity at the physiological...

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Detalles Bibliográficos
Autores principales: Boikov, Dina A., Locke, Jeffrey B., James, Kenneth D., Bartizal, Ken, Sobel, Jack D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400080/
https://www.ncbi.nlm.nih.gov/pubmed/28158577
http://dx.doi.org/10.1093/jac/dkx008