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Effect of the glucocorticoid receptor antagonist RU486 on MK-801 induced behavioural sensitisation

Stress is known to modulate sensitisation to repeated psychostimulant exposure. However, there is no direct evidence linking glucocorticoids and sensitisation achieved by repeated administration of the NMDA receptor antagonist MK-801. We tested the hypothesis that co-administration of RU486, a gluco...

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Detalles Bibliográficos
Autores principales: Lefevre, Emilia M., Medley, Gregory A., Reeks, Timothy, Alexander, Suzy, Burne, Thomas H. J., Eyles, Darryl W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400269/
https://www.ncbi.nlm.nih.gov/pubmed/28430805
http://dx.doi.org/10.1371/journal.pone.0176156