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Quantification of hypoxia-related gene expression as a potential approach for clinical outcome prediction in breast cancer
Breast cancers are solid tumors frequently characterized by regions with low oxygen concentrations. Cellular adaptations to hypoxia are mainly determined by “hypoxia inducible factors” that mediate transcriptional modifications involved in drug resistance and tumor progression leading to metastasis...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400273/ https://www.ncbi.nlm.nih.gov/pubmed/28430808 http://dx.doi.org/10.1371/journal.pone.0175960 |