Cargando…

Quantification of hypoxia-related gene expression as a potential approach for clinical outcome prediction in breast cancer

Breast cancers are solid tumors frequently characterized by regions with low oxygen concentrations. Cellular adaptations to hypoxia are mainly determined by “hypoxia inducible factors” that mediate transcriptional modifications involved in drug resistance and tumor progression leading to metastasis...

Descripción completa

Detalles Bibliográficos
Autores principales:	El Guerrab, Abderrahim, Cayre, Anne, Kwiatkowski, Fabrice, Privat, Maud, Rossignol, Jean-Marc, Rossignol, Fabrice, Penault-Llorca, Frédérique, Bignon, Yves-Jean
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400273/ https://www.ncbi.nlm.nih.gov/pubmed/28430808 http://dx.doi.org/10.1371/journal.pone.0175960

Ejemplares similares

Differential Impact of EGFR-Targeted Therapies on Hypoxia Responses: Implications for Treatment Sensitivity in Triple-Negative Metastatic Breast Cancer
por: El Guerrab, Abderrahim, et al.
Publicado: (2011)

Anti-EGFR monoclonal antibodies and EGFR tyrosine kinase inhibitors as combination therapy for triple-negative breast cancer
por: Guerrab, Abderrahim El, et al.
Publicado: (2016)

aHIF but not HIF-1α transcript is a poor prognostic marker in human breast cancer
por: Cayre, Anne, et al.
Publicado: (2003)

Co-targeting EGFR and mTOR with gefitinib and everolimus in triple-negative breast cancer cells
por: El Guerrab, Abderrahim, et al.
Publicado: (2020)

ERCC1 and telomere status in breast tumours treated with neoadjuvant chemotherapy and their association with patient prognosis
por: Gay‐Bellile, Mathilde, et al.
Publicado: (2016)

BRCA1 Induces Major Energetic Metabolism Reprogramming in Breast Cancer Cells
por: Privat, Maud, et al.
Publicado: (2014)

TERT promoter status and gene copy number gains: effect on TERT expression and association with prognosis in breast cancer
por: Gay-Bellile, Mathilde, et al.
Publicado: (2017)

Identification of miR-10b, miR-26a, miR-146a and miR-153 as potential triple-negative breast cancer biomarkers
por: Fkih M’hamed, Insaf, et al.
Publicado: (2015)

Cellular Expression of Cyclooxygenase, Aromatase, Adipokines, Inflammation and Cell Proliferation Markers in Breast Cancer Specimen
por: Basu, Samar, et al.
Publicado: (2015)

Comparison of different commercial kits for HER2 testing in breast cancer: looking for the accurate cutoff for amplification
por: Cayre, Anne, et al.
Publicado: (2007)

Breaking down the Contradictory Roles of Histone Deacetylase SIRT1 in Human Breast Cancer
por: Rifaï, Khaldoun, et al.
Publicado: (2018)

Dual SIRT1 expression patterns strongly suggests its bivalent role in human breast cancer
por: Rifaï, Khaldoun, et al.
Publicado: (2017)

The Epigenetic Landscape of Promoter Genome-wide Analysis in Breast Cancer
por: Karsli-Ceppioglu, Seher, et al.
Publicado: (2017)

SIRT1-dependent epigenetic regulation of H3 and H4 histone acetylation in human breast cancer
por: Rifaï, Khaldoun, et al.
Publicado: (2018)

Analysis of tumour-infiltrating lymphocytes reveals two new biologically different subgroups of breast ductal carcinoma in situ
por: Beguinot, Marie, et al.
Publicado: (2018)

Permanence of the information given during oncogenetic counseling to persons at familial risk of breast/ovarian and/or colon cancer
por: Kwiatkowski, Fabrice, et al.
Publicado: (2012)

BCRP and P-gp relay overexpression in triple negative basal-like breast cancer cell line: a prospective role in resistance to Olaparib
por: Dufour, Robin, et al.
Publicado: (2015)

BRCA Mutations Increase Fertility in Families at Hereditary Breast/Ovarian Cancer Risk
por: Kwiatkowski, Fabrice, et al.
Publicado: (2015)

Antioxydation And Cell Migration Genes Are Identified as Potential Therapeutic Targets in Basal-Like and BRCA1 Mutated Breast Cancer Cell Lines
por: Privat, Maud, et al.
Publicado: (2018)

BRACAVENIR - impact of a psychoeducational intervention on expectations and coping in young women (aged 18–30 years) exposed to a high familial breast/ovarian cancer risk: study protocol for a randomized controlled trial
por: Kwiatkowski, Fabrice, et al.
Publicado: (2016)

A new metabolic gene signature in prostate cancer regulated by JMJD3 and EZH2
por: Daures, Marine, et al.
Publicado: (2018)

The Functions of the Demethylase JMJD3 in Cancer
por: Sanchez, Anna, et al.
Publicado: (2021)

A high expression ratio of RhoA/RhoB is associated with the migratory and invasive properties of basal-like Breast Tumors
por: Privat, Maud, et al.
Publicado: (2020)

La recherche de la surexpression de la protéine et l'amplification du gène HER2 dans le cancer de l'estomac par immunohistochimie et Hybridation in Situ: expérience du CHU HASSAN II de Fès
por: El Fatemi, Hinde, et al.
Publicado: (2012)

Recurrence biomarkers of triple negative breast cancer treated with neoadjuvant chemotherapy and anti-EGFR antibodies
por: Radosevic-Robin, Nina, et al.
Publicado: (2021)

Activation of EGFR, HER2 and HER3 by neurotensin/neurotensin receptor 1 renders breast tumors aggressive yet highly responsive to lapatinib and metformin in mice
por: Dupouy, Sandra, et al.
Publicado: (2014)

Is There a Relationship between Ovarian Epithelial Dysplasia and Infertility?
por: Chene, Gautier, et al.
Publicado: (2012)

Use of Gene Expression Profiles of Peripheral Blood Lymphocytes to Distinguish BRCA1 Mutation Carriers in High Risk Breast Cancer Families
por: Vuillaume, Marie-Laure, et al.
Publicado: (2009)

Global analysis of H3K27me3 as an epigenetic marker in prostate cancer progression
por: Ngollo, Marjolaine, et al.
Publicado: (2017)

Association between hereditary predisposition to common cancers and congenital multimalformations
por: Kwiatkowski, Fabrice, et al.
Publicado: (2019)

Complexité: fondamentaux à l'usage des étudiants et des professionnels
por: Rossignol, Jean-Yves
Publicado: (2018)

DNA repair gene ERCC2 polymorphisms and associations with breast and ovarian cancer risk
por: Bernard-Gallon, Dominique, et al.
Publicado: (2008)

The association between Histone 3 Lysine 27 Trimethylation (H3K27me3) and prostate cancer: relationship with clinicopathological parameters
por: Ngollo, Marjolaine, et al.
Publicado: (2014)

LightSpot(®)-FL-1 Fluorescent Probe: An Innovative Tool for Cancer Drug Resistance Analysis by Direct Detection and Quantification of the P-glycoprotein (P-gp) on Monolayer Culture and Spheroid Triple Negative Breast Cancer Models
por: Goisnard, Antoine, et al.
Publicado: (2021)

Circulating proteins as predictive and prognostic biomarkers in breast cancer
por: Veyssière, Hugo, et al.
Publicado: (2022)

Early Onset Multiple Primary Tumors in Atypical Presentation of Cowden Syndrome Identified by Whole-Exome-Sequencing
por: Cavaillé, Mathias, et al.
Publicado: (2018)

Effectiveness of a Global Multidisciplinary Supportive and Educational Intervention in Thermal Resort on Anthropometric and Biological Parameters, and the Disease-Free Survival after Breast Cancer Treatment Completion (PACThe)
por: Vasson, Marie-Paule, et al.
Publicado: (2020)

PROCURE European consensus on breast cancer multigene signatures in early breast cancer management
por: Curigliano, Giuseppe, et al.
Publicado: (2023)

Telomere Status of Advanced Non-Small-Cell Lung Cancer Offers a Novel Promising Prognostic and Predictive Biomarker
por: Faugeras, Eve, et al.
Publicado: (2022)

Frequent EGFR Positivity and Overexpression in High-Grade Areas of Human MPNSTs
por: Tabone-Eglinger, Séverine, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_fkc07f94vqn1ghsje8n9j5il2d