Oncogenes without a Neighboring Tumor-Suppressor Gene Are More Prone to Amplification

Focal copy number gains or losses are important genomic hallmarks of cancer. The genomic distribution of oncogenes and tumor-suppressor genes (TSG) in relation to focal copy number aberrations is unclear. Our analysis revealed that the mean distance of TSGs from oncogenes was significantly shorter t...

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Detalles Bibliográficos
Autores principales: Wu, William K.K., Li, Xiangchun, Wang, Xiansong, Dai, Rudin Z.W., Cheng, Alfred S.L., Wang, Maggie H.T., Kwong, Thomas, Chow, Tai C., Yu, Jun, Chan, Matthew T.V., Wong, Sunny H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Discoveries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400371/
https://www.ncbi.nlm.nih.gov/pubmed/28087780
http://dx.doi.org/10.1093/molbev/msw295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400371/
https://www.ncbi.nlm.nih.gov/pubmed/28087780
http://dx.doi.org/10.1093/molbev/msw295

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