Both Maintenance and Avoidance of RNA-Binding Protein Interactions Constrain Coding Sequence Evolution

While the principal force directing coding sequence (CDS) evolution is selection on protein function, to ensure correct gene expression CDSs must also maintain interactions with RNA-binding proteins (RBPs). Understanding how our genes are shaped by these RNA-level pressures is necessary for diagnost...

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Detalles Bibliográficos
Autores principales: Savisaar, Rosina, Hurst, Laurence D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Discoveries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400389/
https://www.ncbi.nlm.nih.gov/pubmed/28138077
http://dx.doi.org/10.1093/molbev/msx061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400389/
https://www.ncbi.nlm.nih.gov/pubmed/28138077
http://dx.doi.org/10.1093/molbev/msx061

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