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Both Maintenance and Avoidance of RNA-Binding Protein Interactions Constrain Coding Sequence Evolution
While the principal force directing coding sequence (CDS) evolution is selection on protein function, to ensure correct gene expression CDSs must also maintain interactions with RNA-binding proteins (RBPs). Understanding how our genes are shaped by these RNA-level pressures is necessary for diagnost...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400389/ https://www.ncbi.nlm.nih.gov/pubmed/28138077 http://dx.doi.org/10.1093/molbev/msx061 |