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Differential Gene Expression in the Human Brain Is Associated with Conserved, but Not Accelerated, Noncoding Sequences

Previous studies have found that genes which are differentially expressed within the developing human brain disproportionately neighbor conserved noncoding sequences (CNSs) that have an elevated substitution rate in humans and in other species. One explanation for this general association of differe...

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Detalles Bibliográficos
Autores principales: Meyer, Kyle A., Marques-Bonet, Tomas, Sestan, Nenad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400397/
https://www.ncbi.nlm.nih.gov/pubmed/28204568
http://dx.doi.org/10.1093/molbev/msx076