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Inositol polyphosphate multikinase promotes Toll-like receptor–induced inflammation by stabilizing TRAF6
Toll-like receptor (TLR) signaling is tightly controlled to protect hosts from microorganisms while simultaneously preventing uncontrolled immune responses. Tumor necrosis factor receptor–associated factor 6 (TRAF6) is a critical mediator of TLR signaling, but the precise mechanism of how TRAF6 prot...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400429/ https://www.ncbi.nlm.nih.gov/pubmed/28439546 http://dx.doi.org/10.1126/sciadv.1602296 |