Inositol polyphosphate multikinase promotes Toll-like receptor–induced inflammation by stabilizing TRAF6

Toll-like receptor (TLR) signaling is tightly controlled to protect hosts from microorganisms while simultaneously preventing uncontrolled immune responses. Tumor necrosis factor receptor–associated factor 6 (TRAF6) is a critical mediator of TLR signaling, but the precise mechanism of how TRAF6 prot...

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Detalles Bibliográficos
Autores principales: Kim, Eunha, Beon, Jiyoon, Lee, Seulgi, Park, Seung Ju, Ahn, Hyoungjoon, Kim, Min Gyu, Park, Jeong Eun, Kim, Wooseob, Yuk, Jae-Min, Kang, Suk-Jo, Lee, Seung-Hyo, Jo, Eun-Kyeong, Seong, Rho Hyun, Kim, Seyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400429/
https://www.ncbi.nlm.nih.gov/pubmed/28439546
http://dx.doi.org/10.1126/sciadv.1602296

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