Ezrin activation by LOK phosphorylation involves a PIP(2)-dependent wedge mechanism

How cells specify morphologically distinct plasma membrane domains is poorly understood. Prior work has shown that restriction of microvilli to the apical aspect of epithelial cells requires the localized activation of the membrane-F-actin linking protein ezrin. Using an in vitro system, we now defi...

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Detalles Bibliográficos
Autores principales: Pelaseyed, Thaher, Viswanatha, Raghuvir, Sauvanet, Cécile, Filter, Joshua J, Goldberg, Michael L, Bretscher, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400502/
https://www.ncbi.nlm.nih.gov/pubmed/28430576
http://dx.doi.org/10.7554/eLife.22759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400502/
https://www.ncbi.nlm.nih.gov/pubmed/28430576
http://dx.doi.org/10.7554/eLife.22759

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