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Ezrin activation by LOK phosphorylation involves a PIP(2)-dependent wedge mechanism
How cells specify morphologically distinct plasma membrane domains is poorly understood. Prior work has shown that restriction of microvilli to the apical aspect of epithelial cells requires the localized activation of the membrane-F-actin linking protein ezrin. Using an in vitro system, we now defi...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400502/ https://www.ncbi.nlm.nih.gov/pubmed/28430576 http://dx.doi.org/10.7554/eLife.22759 |