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Level of FACT defines the transcriptional landscape and aggressive phenotype of breast cancer cells

Although breast cancer (BrCa) may be detected at an early stage, there is a shortage of markers that predict tumor aggressiveness and a lack of targeted therapies. Histone chaperone FACT, expressed in a limited number of normal cells, is overexpressed in different types of cancer, including BrCa. Re...

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Detalles Bibliográficos
Autores principales: Fleyshman, Daria, Prendergast, Laura, Safina, Alfiya, Paszkiewicz, Geraldine, Commane, Mairead, Morgan, Kelsey, Attwood, Kristopher, Gurova, Katerina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400524/
https://www.ncbi.nlm.nih.gov/pubmed/28423528
http://dx.doi.org/10.18632/oncotarget.15656