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Systematic functional perturbations uncover a prognostic genetic network driving human breast cancer

Prognostic classifiers conceivably comprise biomarker genes that functionally contribute to the oncogenic and metastatic properties of cancer, but this has not been investigated systematically. The transcription factor Fra-1 not only has an essential role in breast cancer, but also drives the expres...

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Detalles Bibliográficos
Autores principales: Gallenne, Tristan, Ross, Kenneth N., Visser, Nils L., Salony, Desmet, Christophe J., Wittner, Ben S., Wessels, Lodewyk F.A., Ramaswamy, Sridhar, Peeper, Daniel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400527/
https://www.ncbi.nlm.nih.gov/pubmed/28411283
http://dx.doi.org/10.18632/oncotarget.16244