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Metformin-treated cancer cells modulate macrophage polarization through AMPK-NF-κB signaling
Accumulating evidence is indicating metformin to possess the potential ability in preventing tumor development and suppressing cancer growth. However, the exact mechanism of its antitumorigenic effects is still not clear. We found that metformin suppressed the ability of cancer to skew macrophage to...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400538/ https://www.ncbi.nlm.nih.gov/pubmed/28157701 http://dx.doi.org/10.18632/oncotarget.14982 |