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Metformin-treated cancer cells modulate macrophage polarization through AMPK-NF-κB signaling

Accumulating evidence is indicating metformin to possess the potential ability in preventing tumor development and suppressing cancer growth. However, the exact mechanism of its antitumorigenic effects is still not clear. We found that metformin suppressed the ability of cancer to skew macrophage to...

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Detalles Bibliográficos
Autores principales: Chiang, Chi-Fu, Chao, Ting-Ting, Su, Yu-Fu, Hsu, Chia-Chen, Chien, Chu-Yen, Chiu, Kuo-Chou, Shiah, Shine-Gwo, Lee, Chien-Hsing, Liu, Shyun-Yeu, Shieh, Yi-Shing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400538/
https://www.ncbi.nlm.nih.gov/pubmed/28157701
http://dx.doi.org/10.18632/oncotarget.14982