Exclusive destruction of mitotic spindles in human cancer cells

We identified target proteins modified by phenanthrenes that cause exclusive eradication of human cancer cells. The cytotoxic activity of the phenanthrenes in a variety of human cancer cells is attributed by these findings to post translational modifications of NuMA and kinesins HSET/kifC1 and kif18...

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Detalles Bibliográficos
Autores principales: Visochek, Leonid, Castiel, Asher, Mittelman, Leonid, Elkin, Michael, Atias, Dikla, Golan, Talia, Izraeli, Shai, Peretz, Tamar, Cohen-Armon, Malka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400547/
https://www.ncbi.nlm.nih.gov/pubmed/28209915
http://dx.doi.org/10.18632/oncotarget.15343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400547/
https://www.ncbi.nlm.nih.gov/pubmed/28209915
http://dx.doi.org/10.18632/oncotarget.15343

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