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Diabetic concentrations of metformin inhibit platelet-mediated ovarian cancer cell progression

Clinical studies have suggested a survival benefit in ovarian cancer patients with type 2 diabetes mellitus taking metformin, however the mechanism by which diabetic concentrations of metformin could deliver this effect is still poorly understood. Platelets not only represent an important reservoir...

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Detalles Bibliográficos
Autores principales: Erices, Rafaela, Cubillos, Sofía, Aravena, Raúl, Santoro, Felice, Marquez, Monica, Orellana, Renan, Ramírez, Carolina, González, Pamela, Fuenzalida, Patricia, Bravo, María Loreto, Oliva, Bárbara, Kato, Sumie, Ibañez, Carolina, Brañes, Jorge, Bravo, Erasmo, Alonso, Catalina, García, Karen, Arab, Clemente, Torres, Vicente A., Godoy, Alejandro S., Pereira, Jaime, Bustos, Galdo, Cardenas, Julio Cesar, Cuello, Mauricio A., Owen, Gareth I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400552/
https://www.ncbi.nlm.nih.gov/pubmed/28209916
http://dx.doi.org/10.18632/oncotarget.15348