mTOR inhibitors activate PERK signaling and favor viability of gastrointestinal neuroendocrine cell lines

mTOR and Unfolded Protein Response (UPR) are two signaling pathways frequently activated in cancer cells. The mTOR pathway has been shown to be up-regulated in most gastroenteropancreatic neuroendocrine tumors. In contrast, little is known about the UPR status in neoplastic neuroendocrine cells. How...

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Detalles Bibliográficos
Autores principales: Freis, Patricia, Bollard, Julien, Lebeau, Justine, Massoma, Patrick, Fauvre, Joëlle, Vercherat, Cécile, Walter, Thomas, Manié, Serge, Roche, Colette, Scoazec, Jean-Yves, Ferraro-Peyret, Carole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400559/
https://www.ncbi.nlm.nih.gov/pubmed/28423496
http://dx.doi.org/10.18632/oncotarget.15469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400559/
https://www.ncbi.nlm.nih.gov/pubmed/28423496
http://dx.doi.org/10.18632/oncotarget.15469

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