Imidazoline I(2) receptor inhibitor idazoxan regulates the progression of hepatic fibrosis via Akt-Nrf2-Smad2/3 signaling pathway

Liver fibrosis is a global health problem and its relationship with imidazoline I(2) receptor has not been reported. This study aimed to investigate the effects and underlying mechanisms of imidazoline I(2) receptor (I(2)R) inhibitor idazoxan (IDA) on carbon tetrachloride (CCl(4))-induced liver fibr...

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Detalles Bibliográficos
Autores principales: Xuanfei, Li, Hao, Chen, Zhujun, Yi, Yanming, Liu, Jianping, Gong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400562/
https://www.ncbi.nlm.nih.gov/pubmed/28423499
http://dx.doi.org/10.18632/oncotarget.15472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400562/
https://www.ncbi.nlm.nih.gov/pubmed/28423499
http://dx.doi.org/10.18632/oncotarget.15472

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