Relaxin abrogates renal interstitial fibrosis by regulating macrophage polarization via inhibition of Toll-like receptor 4 signaling

Renal fibrosis is a common feature of chronic kidney disease (CKD). To inhibit the CKD process, it is important to prevent renal fibrosis, though CKD remains incurable. Renal fibrosis can be inhibited by relaxin in several experimental models, but the mechanism of relaxin for antifibrotic potential...

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Detalles Bibliográficos
Autores principales: Chen, Lei, Sha, Ming-Lei, Li, Deng, Zhu, Yi-Ping, Wang, Xing-Jie, Jiang, Chen-Yi, Xia, Shu-Jie, Shao, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400564/
https://www.ncbi.nlm.nih.gov/pubmed/28416741
http://dx.doi.org/10.18632/oncotarget.15483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400564/
https://www.ncbi.nlm.nih.gov/pubmed/28416741
http://dx.doi.org/10.18632/oncotarget.15483

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