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TRAP1 protein signature predicts outcome in human metastatic colorectal carcinoma

TRAP1 is a HSP90 molecular chaperone upregulated in colorectal carcinomas and involved in control of intracellular signaling, cell cycle, apoptosis and drug resistance, stemness and bioenergetics through co-traslational regulation of a network of client proteins. Thus, the clinical significance of T...

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Detalles Bibliográficos
Autores principales: Maddalena, Francesca, Simeon, Vittorio, Vita, Giulia, Bochicchio, Annamaria, Possidente, Luciana, Sisinni, Lorenza, Lettini, Giacomo, Condelli, Valentina, Matassa, Danilo Swann, Bergolis, Valeria Li, Fersini, Alberto, Romito, Sante, Aieta, Michele, Ambrosi, Antonio, Esposito, Franca, Land riscina, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400579/
https://www.ncbi.nlm.nih.gov/pubmed/28177905
http://dx.doi.org/10.18632/oncotarget.15070