Identification and analysis of mutational hotspots in oncogenes and tumour suppressors

BACKGROUND: The key to interpreting the contribution of a disease-associated mutation in the development and progression of cancer is an understanding of the consequences of that mutation both on the function of the affected protein and on the pathways in which that protein is involved. Protein doma...

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Detalles Bibliográficos
Autores principales: Baeissa, Hanadi, Benstead-Hume, Graeme, Richardson, Christopher J., Pearl, Frances M.G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400584/
https://www.ncbi.nlm.nih.gov/pubmed/28423505
http://dx.doi.org/10.18632/oncotarget.15514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400584/
https://www.ncbi.nlm.nih.gov/pubmed/28423505
http://dx.doi.org/10.18632/oncotarget.15514

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