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Identification and analysis of mutational hotspots in oncogenes and tumour suppressors
BACKGROUND: The key to interpreting the contribution of a disease-associated mutation in the development and progression of cancer is an understanding of the consequences of that mutation both on the function of the affected protein and on the pathways in which that protein is involved. Protein doma...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400584/ https://www.ncbi.nlm.nih.gov/pubmed/28423505 http://dx.doi.org/10.18632/oncotarget.15514 |