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miR-494-3p overexpression promotes megakaryocytopoiesis in primary myelofibrosis hematopoietic stem/progenitor cells by targeting SOCS6

Primary myelofibrosis (PMF) is a chronic Philadelphia-negative myeloproliferative neoplasm characterized by hematopoietic stem cell-derived clonal myeloproliferation, involving especially the megakaryocyte lineage. To better characterize how the altered expression of microRNAs might contribute to PM...

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Detalles Bibliográficos
Autores principales: Rontauroli, Sebastiano, Norfo, Ruggiero, Pennucci, Valentina, Zini, Roberta, Ruberti, Samantha, Bianchi, Elisa, Salati, Simona, Prudente, Zelia, Rossi, Chiara, Rosti, Vittorio, Guglielmelli, Paola, Barosi, Giovanni, Vannucchi, Alessandro, Tagliafico, Enrico, Manfredini, Rossella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400591/
https://www.ncbi.nlm.nih.gov/pubmed/28423484
http://dx.doi.org/10.18632/oncotarget.15226