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NRIP/DCAF6 stabilizes the androgen receptor protein by displacing DDB2 from the CUL4A-DDB1 E3 ligase complex in prostate cancer

Both nuclear receptor interaction protein (NRIP) and DNA damage binding protein 2 (DDB2) belong to the Cullin 4 (CUL4)-DDB1 binding protein family and are androgen receptor (AR)-interacting proteins. Here, we investigated the expression patterns of the NRIP, DDB2 and AR proteins in human prostate ca...

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Detalles Bibliográficos
Autores principales: Chen, Hsin-Hsiung, Fan, Ping, Chang, Szu-Wei, Tsao, Yeou-Ping, Huang, Hsiang-Po, Chen, Show-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400601/
https://www.ncbi.nlm.nih.gov/pubmed/28212551
http://dx.doi.org/10.18632/oncotarget.15308