TGF-β–independent CTGF induction regulates cell adhesion mediated drug resistance by increasing collagen I in HCC

Hepatocellular carcinoma (HCC) is resistant to conventional chemotherapeutic agents and remains an unmet medical need. Here, we demonstrate a mechanism of cell adhesion-mediated drug resistance using a variety of HCC spheroid models to overcome environment-mediated drug resistance in HCC. We classif...

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Detalles Bibliográficos
Autores principales: Song, Yeonhwa, Kim, Jin-Sun, Choi, Eun Kyung, Kim, Joon, Kim, Kang Mo, Seo, Haeng Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400613/
https://www.ncbi.nlm.nih.gov/pubmed/28423507
http://dx.doi.org/10.18632/oncotarget.15521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400613/
https://www.ncbi.nlm.nih.gov/pubmed/28423507
http://dx.doi.org/10.18632/oncotarget.15521

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