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ATM kinase sustains breast cancer stem-like cells by promoting ATG4C expression and autophagy

The efficacy of Ataxia-Telangiectasia Mutated (ATM) kinase signalling inhibition in cancer therapy is tempered by the identification of new emerging functions of ATM, which suggests that the role of this protein in cancer progression is complex. We recently demonstrated that this tumor suppressor ge...

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Detalles Bibliográficos
Autores principales: Antonelli, Martina, Strappazzon, Flavie, Arisi, Ivan, Brandi, Rossella, D’Onofrio, Mara, Sambucci, Manolo, Manic, Gwenola, Vitale, Ilio, Barilà, Daniela, Stagni, Venturina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400616/
https://www.ncbi.nlm.nih.gov/pubmed/28423511
http://dx.doi.org/10.18632/oncotarget.15537