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miR-503-5p confers drug resistance by targeting PUMA in colorectal carcinoma

The development of multidrug-resistance (MDR) is a major contributor to death in colorectal carcinoma (CRC). Here, we investigated the possible role of microRNA (miR)-503-5p in drug resistant CRC cells. Unbiased microRNA array screening revealed that miR-503-5p is up-regulated in two oxaliplatin (OX...

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Detalles Bibliográficos
Autores principales: Xu, Ke, Chen, Guo, Qiu, Yanyan, Yuan, Zeting, Li, Hongchang, Yuan, Xia, Sun, Jian, Xu, Jianhua, Liang, Xin, Yin, Peihao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400618/
https://www.ncbi.nlm.nih.gov/pubmed/28423513
http://dx.doi.org/10.18632/oncotarget.15559