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DNA methylation intratumor heterogeneity in localized lung adenocarcinomas

Cancers are composed of cells with distinct molecular and phenotypic features within a given tumor, a phenomenon termed intratumor heterogeneity (ITH). Previously, we have demonstrated genomic ITH in localized lung adenocarcinomas; however, the nature of methylation ITH in lung cancers has not been...

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Detalles Bibliográficos
Autores principales: Quek, Kelly, Li, Jun, Estecio, Marcos, Zhang, Jiexin, Fujimoto, Junya, Roarty, Emily, Little, Latasha, Chow, Chi-Wan, Song, Xingzhi, Behrens, Carmen, Chen, Taiping, William, William N., Swisher, Stephen, Heymach, John, Wistuba, Ignacio, Zhang, Jianhua, Futreal, Andrew, Zhang, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400640/
https://www.ncbi.nlm.nih.gov/pubmed/28423542
http://dx.doi.org/10.18632/oncotarget.15777