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MiR-519d impedes cisplatin-resistance in breast cancer stem cells by down-regulating the expression of MCL-1

Cancer stem cells are considered as the cell population which is responsible for chemoresistance and treatment failure in breast cancer patients. Therefore, it is urgent to explore the mechanism by which cancer stem cells survive under the treatment of chemotherapeutic drugs such as cisplatin. In th...

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Detalles Bibliográficos
Autores principales: Xie, Qing, Wang, Shuai, Zhao, Yue, Zhang, Zhenchao, Qin, Chuan, Yang, Xianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400641/
https://www.ncbi.nlm.nih.gov/pubmed/28423543
http://dx.doi.org/10.18632/oncotarget.15781