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The Blood-Brain Barrier: Clinical Implications for Drug Delivery to the Brain

The blood-brain barrier (BBB) determines whether or not a given drug can reach the central nervous system (CNS), either by passive diffusion or through carrier or receptor systems. Initial work focused on the structural and physico-chemical requirements favouring transport across the BBB as related...

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Detalles Bibliográficos
Autores principales: De Boer, A G, Breimer, D D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal College of Physicians of London 1994
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5401103/
https://www.ncbi.nlm.nih.gov/pubmed/7884704