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The Blood-Brain Barrier: Clinical Implications for Drug Delivery to the Brain
The blood-brain barrier (BBB) determines whether or not a given drug can reach the central nervous system (CNS), either by passive diffusion or through carrier or receptor systems. Initial work focused on the structural and physico-chemical requirements favouring transport across the BBB as related...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal College of Physicians of London
1994
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5401103/ https://www.ncbi.nlm.nih.gov/pubmed/7884704 |