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Lupus in the Fas Lane?
Fas is a 43 kDa glycoprotein molecule which is involved in inducing apoptosis in both B and T lymphocytes. In the murine MRL/lpr-lpr model of systemic lupus erythematosus (SLE), the lymphoproliferation (lpr) mutation results in defective transcription of the gene that codes for the Fas protein. MRL...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal College of Physicians of London
1995
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5401240/ https://www.ncbi.nlm.nih.gov/pubmed/8748102 |