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Lupus in the Fas Lane?

Fas is a 43 kDa glycoprotein molecule which is involved in inducing apoptosis in both B and T lymphocytes. In the murine MRL/lpr-lpr model of systemic lupus erythematosus (SLE), the lymphoproliferation (lpr) mutation results in defective transcription of the gene that codes for the Fas protein. MRL...

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Detalles Bibliográficos
Autor principal: Singh, Ajay K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal College of Physicians of London 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5401240/
https://www.ncbi.nlm.nih.gov/pubmed/8748102