A highly pathogenic simian/human immunodeficiency virus effectively produces infectious virions compared with a less pathogenic virus in cell culture

BACKGROUND: The host range of human immunodeficiency virus (HIV) is quite narrow. Therefore, analyzing HIV-1 pathogenesis in vivo has been limited owing to lack of appropriate animal model systems. To overcome this, chimeric simian and human immunodeficiency viruses (SHIVs) that encode HIV-1 Env and...

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Detalles Bibliográficos
Autores principales: Iwanami, Shoya, Kakizoe, Yusuke, Morita, Satoru, Miura, Tomoyuki, Nakaoka, Shinji, Iwami, Shingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5401468/
https://www.ncbi.nlm.nih.gov/pubmed/28431573
http://dx.doi.org/10.1186/s12976-017-0055-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5401468/
https://www.ncbi.nlm.nih.gov/pubmed/28431573
http://dx.doi.org/10.1186/s12976-017-0055-8

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